Professor Dr. Riaz Ahmad Bhutta Dr. Naheed Afroz Syed, Dr.
Rheumatoid factor RF is a protein made by your immune system that can attack healthy tissue in your body. So, the presence of RF in your blood can indicate that you have an autoimmune disease. Sometimes people without any medical problems produce a small amount of RF.
Steuer, J. Watkins, F. Smith, L.
Paulo 57 5 : Ages ranged from 2. The control group consisted of 45 healthy children. The detection of immunoglobulin E-rheumatoid factor was carried out utilizing an enzyme-linked immunosorbent assay.
Rheumatoid factor RF is the autoantibody that was first found in rheumatoid arthritis. Rheumatoid factor can also be a cryoglobulin antibody that precipitates on cooling of a blood sample ; it can be either type 2 monoclonal IgM to polyclonal IgG or type 3 polyclonal IgM to polyclonal IgG cryoglobulin. Although predominantly encountered as IgM, rheumatoid factor can be of any isotype of immunoglobulinsi.
Skip to search form Skip to main content. Rheumatoid factor: a cause of fals positive histoplasmin latex agglutination. Oxenhandler and Edward H.
What does it mean to have a positive rheumatoid factor RF? Does this mean that you have rheumatoid arthritisare you at risk of developing rheumatoid arthritis, is your prognosis worse, or is it completely unrelated to arthritis? Before answering, what is a positive rheumatoid factor, we need to understand antibodies and how they are made.
Rheumatoid arthritis RA is a chronic autoimmune disease that primarily affects the joints, but can affect other parts of the body. Diagnosing and managing RA involves clinical evaluation by a rheumatologist, as well as several different laboratory tests that require blood work. The results of these tests may be used in two ways:. The doctor and healthcare team use the results of these tests to guide treatment options for each patient.
A rheumatoid factor test measures the amount of rheumatoid factor in your blood. Rheumatoid factors are proteins produced by your immune system that can attack healthy tissue in your body. High levels of rheumatoid factor in the blood are most often associated with autoimmune diseases, such as rheumatoid arthritis and Sjogren's syndrome.